Battelle Memorial Institute Molecular Research Associate in Frederick, Maryland

Battelle is guided by a founding mission. We invest our knowledge, talents and resources, helping our customers achieve their most important goals. We apply scientific rigor and creativity, succeeding where others may fail, and we invest in our communities, making the world better for generations to come. All of us share a common purpose: to solve the greatest challenges of today and tomorrow.

Our 22,000 employees work at the forefront of scientific innovation to tackle critical challenges in security, human health, manufacturing, energy and environmental management. Battelle’s work is grounded in the belief that science, technology and a passion for excellence can make industries more competitive and the world a better place.

We are currently seeking a Molecular Research Associate. This position is located located at Fort Detrick in Frederick, Maryland.

Job Description

The Molecular Research Associate will support government-approved research by providing technical support to characterize host-pathogen interactions, and develop medical countermeasures to high consequence pathogens. investigating host/pathogen interactions of high consequence viral pathogens at the National Institutes of Allergy and Infectious Diseases (NIAID) Integrated Research Facility located at Fort Detrick in Frederick, Maryland . Working within an existing team, the technician will perform and analyze microbiology and virology based assays. He/she will be responsible for proficiency in the use and maintenance of all equipment and procedures for the assigned area with ability to cross-train in related support areas.

Major Responsibilities:

  • Virology assays to include but not limited to titration by TCID50 and plaque assays

  • DNA/RNA extraction, purification, quantification, transcription, replication, amplification, and mutagenesis, PCR/real-time PCR, microarray

  • Analysis of viral load in blood and tissue samples using quantitative real time PCR (one-step and two-step assays)

  • QC analysis of viral samples including endotoxin, mycoplasma and sterility testing.

  • Implement assays per well-documented standards and contribute to the development of standard methods

  • Effectively manage tasks and can rapidly adjust to changing experimental priorities

  • Routinely work in high containment laboratories

  • General lab safety, organization, and maintenance

  • Maintain freezer and reagent inventories, common lab stocks, and lab equipment

  • Prepare packages for shipment

  • Maintain PCR primer, probe and standards inventories

  • Prepare analyzed data

  • Participate in general laboratory housekeeping, to include biohazard waste management

  • Provide support in preparing graphs and figures for publication using Excel and Graphpad Prism.

  • ABI 7500 Dx Real Time PCR Acquisition and Analysis software.

  • Primer/Probe design software such as Primer Express or Seqbuilder.

  • Basic understanding of laboratory information management systems (LIMS)

  • Performs assignments by compiling and evaluating design and test data, preparing technical specifications, analyzing technical data to determine appropriate limits and variables for product, process or materials specifications.

  • Interprets results and writes small sections of technical reports.

  • Troubleshoots the testing process when expected results are not obtained. Recommends paths forward to resolve analysis problems.

THE FOLLOWING IS REQUIRED TO BE CONSIDERED FOR THIS POSITION:

  • Must be a US citizen or permanent resident.

  • Bachelor’s degree in the biological sciences with 0-2 years of experience.

  • Previous laboratory experience including basic understanding of design, optimization and implementation of quantitative PCR assays.

  • Excellent interpersonal skills, excellent oral and written communication and organizational skills, ability to work independently, design experiments, and analyze data are required

  • Ability to obtain/maintain certification in Chemical Personnel Reliability Program and/or Biological Personnel Reliability Program.

  • Ability to obtain/maintain CDC Select Agent Program approval.

  • Ability to obtain/maintain DoJ Security Risk Assessment (SRA) approval.

  • Must be willing to work in a biosafety level 2 (BSL2) and/or 3 (BSL3) and/or 4 (BSL 4) environment and able to wear appropriate respiratory protection.

  • Must be willing to be immunized with licensed and FDA approved Investigational New Drugs (IND) recommended for persons at risk to occupational exposure of biological agents

  • Must be willing to participate in periodic drug screening.

  • Individual must be able to meet the requirements for Public Trust Level 5b

THE FOLLOWING IS DESIRED AND NOT REQUIRED TO BE CONSIDERED FOR THIS POSITION:

  • Previous BSL-3 or BSL-4 containment experience

  • Experience with viral Select Agents is highly desired

Legal Disclaimer

The above statements are intended to describe the nature and level of work being performed by people assigned to this job. They are not intended to be an exhaustive list of all responsibilities, activities and skills required of staff members. No statement herein is intended to imply any authorities to commit Battelle unless special written permission is granted by Battelle's Legal Department.

BENEFITS

Battelle’s competitive benefits program includes comprehensive medical and dental care, matching 401K, paid time off, flexible spending accounts, disability coverage, and other benefits that help provide financial protection for you and your family.

Battelle provides employment and opportunities for advancement, compensation, training, and growth according to individual merit, without regard to race, color, religion, sex (including pregnancy), national origin, sexual orientation, gender identity, marital status, age, genetic information, disability, veteran-status, or any other characteristic protected under applicable Federal, state, or local law. Our goal is for each staff member to have the opportunity to grow to the limits of their abilities and to achieve personal and organizational objectives. We will support positive programs for equal treatment of all staff and full utilization of all qualified employees at all levels within Battelle.

For more information about our other openings, please visit www.battelle.org/careers